Drugs & Vitamins

Idursulfase infusion Active Ingredients: Idursulfase infusion Representative Names: Elaprase Solution for Injection What is Idursulfase infusion? What should I tell my health care provider before I take this medicine? How should this medicine be used? What if I miss a dose? What drug(s) may interact with Idursulfase? What side effects may I notice from receiving Idursulfase? What should I watch for while taking Idursulfase? Where can I keep my medicine? What is Idursulfase infusion? (Back to top) IDURSULFASE (Elaprase®) is a drug that is used to replace an enzyme that is missing in patients with Hunter syndrome, which is also known as mucopolysaccharidosis II. Because of a lack of this enzyme, certain substances are not removed from the cells of the body. The medicine may help relieve some symptoms of Hunter syndrome. The medicine is not a cure. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •an infection or fever •lung disease •an unusual reaction to idursulfase, other medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should this medicine be used? (Back to top) The medicine is for injection into a vein. It is given as an infusion by a health care professional in a hospital or clinic setting. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. While this drug may be prescribed for children as young as 5 years for selected conditions, precautions do apply. What if I miss a dose? (Back to top) It is important to receive the medicine on the schedule developed by your health care provider. If you cannot make an appointment to receive your medicine, call your provider to reschedule as soon as possible. What drug(s) may interact with Idursulfase? (Back to top) Interactions are not expected. What side effects may I notice from receiving Idursulfase? (Back to top) Side effects that you should report to your doctor or health care professional as soon as possible: •allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue •changes in vision •chest pain or chest tightness •fever or chills •seizures •shortness of breath or difficulty breathing Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): •anxiety •headache •heartburn or upset stomach •muscle or joint pain What should I watch for while taking Idursulfase? (Back to top) Visit your prescriber or health care professional for regular checks on your progress. Where can I keep my medicine? (Back to top) You will receive the medicine in a clinic setting. You will not take this medicine at home. Last Updated:08/04/2006 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.